新葡萄京官网

曹修岭

新葡萄京官网:作者:时间:2017-11-21点击数:

曹修岭  博士,讲师,林业硕士生导师

研究方向

利用高通量表型组平台开展细胞衰老及抗衰老活性成分机理的研究

学习与工作经历

2017.09-至今 新葡萄京官网 新葡萄京官网 专任教师

2015.08-2017.09 瑞典哥德堡大学 化学与分子生物学系 博士后

2009.09-2015.07 中国农业大学 生物学院 硕博连读

教学工作

研究生:《高级生物化学》《生物学材料与研究方法》

本科生:《衰老的秘密》

科研项目

1.国家自然科学基金青年项目, 32000387,酵母衰老过程中Yhb1生理性聚集对α-synuclein和synphilin-1细胞毒性的影响及其机制研究, 2021.01-2023.12, 24万,主持

2.浙江省自然科学基金青年项目, LQ19C070001, synphilin-1蛋白聚集体在酵母中与线粒体互作的原位结构及其对线粒体功能影响的分析, 2019.01-2021.12, 9万,主持

3.国家自然科学基金青年项目, 31800163, JB6细胞壁的三维结构、组成成分及其在JB6适应碳酸盐胁迫中的作用分析, 2019.01-2021.12, 27万,参与

论文与专著

1.Xuejiao Jin, Xiuling Cao (co-first), Shenkui Liu*, and Beidong Liu*, Functional Roles of Poly(ADP-Ribose) in Stress Granule Formation and Dynamics, Frontiers in Cell and Developmental Biology, 2021, 9: 671780.

2.Xuejiao Jin, Jie Zhang (co-first), Tingting An (co-first), Huihui Zhao, Wenhao Fu, Danqi Li, Shenkui Liu, Xiuling Cao*, and Beidong Liu*, A Genome-Wide Screen in Saccharomyces cerevisiae Reveals a Critical Role for Oxidative Phosphorylation in Cellular Tolerance to Lithium Hexafluorophosphate, Cells, 2021, 10(4): 888.

3.Xiuling Cao, Xuejiao Jin, and Beidong Liu*, Genome-Wide Imaging-Based Phenomic Screening Using Yeast (Saccharomyces cerevisiae) Strain Collections, Methods in Molecular Biology, 2021, 2196:85-95.

4.Xuejiao Jin, Xiuling Cao, and Beidong Liu*, Isolation of Aged Yeast Cells Using Biotin-Streptavidin Affinity Purification. Methods in Molecular Biology, 2021, 2196:223-228.

5.Xiuling Cao, Xuejiao Jin (co-first), Beidong Liu*, The Involvement of Stress Granules in Aging and Aging Associated Diseases, Aging Cell, 2020, 00: e13136.

6.Xiaoxue Ye, Hao Wang, Xiuling Cao, Xuejiao Jin, Fuqiang Cui, Yuanyuan Bu, Hua Liu, Wenwu Wu, Tetsuo Takano, Shenkui Liu*, Transcriptome Profiling of Puccinellia tenuiflora During Seed Germination Under a Long-term Saline-alkali Stress. BMC Genomics, 2019, 20(1):589.

7.Xiaoling Wang, Xiuling Cao (co-first), Min Liu, Ruiqi Zhang, Xin Zhang, Zongyu Gao, Xiaofei Zhao, Kai Xu, Dawei Li, Yongliang Zhang*, Hsc70-2 is required for Beet black scorch virus infection through interaction with replication and capsid proteins, Scientific Reports, 2018, 8(1): 4526.

8.Xuejiao Jin, Xiuling Cao, Xueting Wang, Jun Jiang, Juan Wan, Jean-Francois Laliberte*, Yongliang Zhang*, Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Plant Virus Replication, Frontiers in Plant Science, 2018, 9(57).

9.Xuejiao Jin, Zhihao Jiang, Kun Zhang, Pengfei Wang, Xiuling Cao, Ning Yue, Xueting Wang, Xuan Zhang, Yunqin Li, Dawei Li, Byung-Ho Kang, Yongliang Zhang*, Three-Dimensional Analysis of Chloroplast Structures Associated with Virus Infection, Plant Physiology, 2018, 176(1): 282-294.

10.Ju Zheng, Junsheng Yang, Young-Jun Choe, Xinxin Hao, Xiuling Cao, Qian Zhao, Yuejie Zhang, Vanessa Franssens, F. Ulrich Hartl, Thomas Nyström, Joris Winderickx, Beidong Liu*, Role of the ribosomal quality control machinery in nucleocytoplasmic translocation of polyQ-expanded huntingtin exon-1, Biochemical and Biophysical Research Communications, 2017, 493(1): 708-717.

11.Junsheng Yang, Xinxin Hao, Xiuling Cao, Beidong Liu*, Thomas Nyström*, Spatial sequestration and detoxification of Huntingtin by the ribosome quality control complex. eLife, 2016, 5: e11792.

12.Xiuling Cao, Xuejiao Jin, Xiaofeng Zhang, Ying Li, Chunyan Wang, Xianbing Wang, Jian Hong, Xiaofeng Wang, Dawei Li, Yongliang Zhang*, Morphogenesis of Endoplasmic Reticulum Membrane-Invaginated Vesicles During Beet Black Scorch Virus Infection: Role of Auxiliary Replication Protein and New Implications of Three-Dimensional Architecture, Journal of Virology, 2015, 89(12): 6184-6195.

联系方式

通讯地址:浙江省杭州市临安区武肃街666号智能实验楼S300

邮箱:cxiuling@zafu.edu.cn

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